Interleukin-16 / IL16 (502-631, His-tag) Human Protein
Interleukin-16 / IL16 (502-631, His-tag) human protein, 50 µg
|Description||Interleukin-16 / IL16 (502-631, His-tag) human protein, 50 µg|
|Expression Host||E. coli|
|Expression cDNA Clone or AA Sequence||MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS|
|Predicted MW||13.3 kDa|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|Purity||>90% by SDS - PAGE|
|Buffer||Presentation State: Purified
State: Liquid purified protein
Buffer System: Phosphate buffered saline (pH7.4).
|Preparation||Liquid purified protein|
|Storage||Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
|Stability||Shelf life: one year from despatch.|
|Synonyms||LCF; NIL16; prIL-16; PRIL16|
|Summary||The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]|
|Protein Families||Druggable Genome, Secreted Protein|