IRF5 (176-240, His-tag) Human Protein

CAT#: AR51437PU-N

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Recombinant human IRF5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


Product Datasheet for 'AR51437PU-N'


USD 845.00


Availability*
2 Weeks

Size
    • 100 ug


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Product Data
Description Recombinant human IRF5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSPPTL QPPTLQPPVV LGPPAPDPSP LAPPPGNPAG FRELLSEVLE PGPLPASLPP AGEQLLPDLL I
Tag His-tag
Predicted MW 10.7 kDa
Concentration 0.25 mg/ml (determined by Bradford assay)
Purity > 85 % by SDS - PAGE
Buffer 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
Preparation Liquid purified protein
Reference Data
RefSeq NP_001092097
Locus ID 3663
Cytogenetics 7q32.1
Synonyms SLEB10
Summary This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Dec 2016]
Protein Families Transcription Factors
Protein Pathways Toll-like receptor signaling pathway

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