IRF5 (176-240, His-tag) Human Protein

CAT#: AR51437PU-S

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IRF5 (176-240, His-tag) human recombinant protein, 20 µg



USD 330.00


Availability*
2 Weeks

Size
    • 20 ug


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Specifications

Product Data
Description IRF5 (176-240, His-tag) human recombinant protein, 20 µg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSPPTL QPPTLQPPVV LGPPAPDPSP LAPPPGNPAG FRELLSEVLE PGPLPASLPP AGEQLLPDLL I
Tag His-tag
Predicted MW 10.7 kDa
Concentration 0.25 mg/ml (determined by Bradford assay)
Purity >85% by SDS - PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
Preparation Liquid purified protein
Protein Description Recombinant human IRF5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_001092097
Locus ID 3663
Cytogenetics 7q32.1
Synonyms SLEB10
Summary This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Dec 2016]
Protein Families Transcription Factors
Protein Pathways Toll-like receptor signaling pathway

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