Insulin-like growth factor I / IGF1 (Long R3)

CAT#: AR31185PU-N

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Recombinant Human IGF-I LR3 is a 9.1 kDa, single, non-glycosylated polypeptide chain containing 83 amino acid residues.


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USD 250.00


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    • 1 mg


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Product Data
Description Recombinant Human IGF-I LR3 is a 9.1 kDa, single, non-glycosylated polypeptide chain containing 83 amino acid residues.
Species Human
Expression Host E. coli
Predicted MW 9.1 kDa
Purity > 98 % pure by SDS-PAGE and HPLC analyses
Bioactivity The ED50 was determined by a cell proliferation assay using FDC-P1 cells is = 2.0 ng/ml, corresponding to a specific activity of = 5 x 105 units/mg.
Endotoxin < 0.1 ng per µg (1EU/µg)
Reconstitution Restore in water to a concentration of 0.1-1.0 mg/ml.
This solution can then be diluted into other aqueous buffers and stored at 2-8°C for 1 week or -20°C for future use.
Preparation Lyophilized (sterile filtered) purified protein without additives
Reference Data
RefSeq NP_000609
Locus ID 3479
Cytogenetics 12q23.2
Synonyms IGF-I; IGFI; MGF
Summary The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Dilated cardiomyopathy, Focal adhesion, Glioma, Hypertrophic cardiomyopathy (HCM), Long-term depression, Melanoma, mTOR signaling pathway, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer

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68 Mouse Clones