Insulin-like growth factor I / IGF1 (Long R3) Human Protein

CAT#: AR31185PU-S

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Insulin-like growth factor I / IGF1 (Long R3) human recombinant protein, 0.2 mg



USD 145.00


Availability*
2 Weeks

Size
    • 200 ug


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Specifications

Product Data
Description Insulin-like growth factor I / IGF1 (Long R3) human recombinant protein, 0.2 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA
Predicted MW 9.1 kDa
Purity >98% pure by SDS-PAGE and HPLC analyses
Buffer Presentation State: Purified
State: Lyophilized (sterile filtered) purified protein without additives
Preservative: None
Stabilizer: None
Bioactivity Biological: The ED50 was determined by a cell proliferation assay using FDC-P1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Endotoxin < 0.1 ng per µg (1EU/µg)
Reconstitution Restore in water to a concentration of 0.1-1.0 mg/ml.
This solution can then be diluted into other aqueous buffers and stored at 2-8°C for 1 week or -20°C for future use.
Preparation Lyophilized (sterile filtered) purified protein without additives
Protein Description Recombinant Human IGF-I LR3 is a 9.1 kDa, single, non-glycosylated polypeptide chain containing 83 amino acid residues.
Note Centrifuge the vial prior to opening!
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_000609
Locus ID 3479
Cytogenetics 12q23.2
Synonyms IGF; IGF-I; IGFI; MGF
Summary The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Dilated cardiomyopathy, Focal adhesion, Glioma, Hypertrophic cardiomyopathy (HCM), Long-term depression, Melanoma, mTOR signaling pathway, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer

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