CLIC2 (1-247, His-tag) Human Protein

CAT#: AR09960PU-L

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CLIC2 (1-247, His-tag) human recombinant protein, 0.5 mg


Product Datasheet for 'AR09960PU-L'


USD 845.00


Availability*
2 Weeks

Size
    • 500 ug


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Specifications

Product Data
Description CLIC2 (1-247, His-tag) human recombinant protein, 0.5 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MSGLRPGTQV DPEIELFVKA GSDGESIGNC PFCQRLFMIL WLKGVKFNVT TVDMTRKPEE LKDLAPGTNP PFLVYNKELK TDFIKIEEFL EQTLAPPRYP HLSPKYKESF DVGCNLFAKF SAYIKNTQKE ANKNFEKSLL KEFKRLDDYL NTPLLDEIDP DSAEEPPVSR RLFLDGDQLT LADCSLLPKL NIIKVAAKKY RDFDIPAEFS GVWRYLHNAY AREEFTHTCP EDKEIENTYA NVAKQKS
Tag His-tag
Predicted MW 30.5 kDa
Concentration 1.0 mg/ml (determined by Bradford assay)
Purity >95%
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl and 1mM DTT
Preparation Liquid purified protein
Protein Description Recombinant human CLIC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_001280
Locus ID 1193
Cytogenetics Xq28
Synonyms CLIC2b; MRXS32; XAP121
Summary This gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein plays a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017]
Protein Families Druggable Genome, Ion Channels: Other

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