UBE2A / RAD6A (1-152, His-tag) Human Protein

CAT#: AR09465PU-L

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UBE2A / RAD6A (1-152, His-tag) human recombinant protein, 0.5 mg


Product Datasheet for 'AR09465PU-L'


USD 745.00


Availability*
2 Weeks

Size
    • 500 ug


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Specifications

Product Data
Description UBE2A / RAD6A (1-152, His-tag) human recombinant protein, 0.5 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MGSSHHHHHH SSGLVPRGSH MSTPARRRLM RDFKRLQEDP PAGVSGAPSE NNIMVWNAVI FGPEGTPFED GTFKLTIEFT EEYPNKPPTV RFVSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS PANSQAAQLY QENKREYEKR VSAIVEQSWR DC
Tag His-tag
Predicted MW 19.4 kDa
Concentration 0.5 mg/ml (determined by Bradford assay)
Purity >95% by SDS-PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 20% Glycerol, 1 mM EDTA
Preparation Liquid purified protein
Protein Description Recombinant human UBE2A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_001269090
Locus ID 7319
Cytogenetics Xq24
Synonyms HHR6A; MRXS30; MRXSN; RAD6A; UBC2
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Protein Families Druggable Genome
Protein Pathways Ubiquitin mediated proteolysis

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