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MDC / CCL22 (25-93, His-Tag) Human Protein

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SKU
AR09280PU-N
Recombinant human CCL22/MDC protein
Size:
100 ug
  $355.00
3 Weeks*
Bulk/Customize

Other products for "CCL22 or NM_002990"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MGSSHHHHHH SSGLVPRGSH MGPYGANMED SVCCRDYVRY RLPLRVVKHF YWTSDSCPRP GVVLLTFRDK EICADPRVPW VKMILNKLSQ
Tag His-Tag
Predicted MW 10.3 kDa (90aa) confirmed by MALDI-TOF
Concentration 0.5mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Endotoxin < 1 EU per 1ug of protein (determined by LAL method)
Preparation Liquid purified peptide
Recommended Dilution SDS-PAGE
Protein Description Recombinant human CCL22/MDC, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_002981
Locus ID 6367
UniProt ID O00626
Cytogenetics 16q21
Synonyms C-C motif chemokine ligand 22, CC chemokine STCP-1, MDC 1-69, Macrophage-derived chemokine, MDC, Small-inducible cytokine A22, SCYA22, Stimulated T-cell chemotactic protein 1, ABCD-1, DC/B-CK, A-152E5.1
Summary This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. provided by RefSeq, Sep 2014
Protein Categories Chemokines, Cytokines, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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