VAMP-2 / Synaptobrevin-2 (1-89, His-tag) Human Protein

CAT#: AR09091PU-N

VAMP-2 / Synaptobrevin-2 (1-89, His-tag) human protein, 0.1 mg

Datasheet
SDS

USD 420.00

3 Weeks*

Size
    • 100 ug
Bulk/Customize

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSA TAATAPPAAP AGEGGPPAPP PNLTSNRRLQ QTQAQVDEVV DIMRVNVDKV LERDQKLSEL DDRADALQAG ASQFETSAAKLKRKYW
Tag His-tag
Predicted MW 13.8 kDa
Concentration lot specific
Purity ≥95 by SDS PAGE
Presentation Purified
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: PBS, pH 7.4, 1 mM EDTA
Preparation Liquid purified protein
Protein Description Synaptobrevin 2, amino acids 1-89, fused to His-tag was expressed in E.coli.
Storage Store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_001317054
Locus ID 6844
UniProt ID F8WCA0
Cytogenetics 17p13.1
Synonyms NEDHAHM; SYB2; VAMP-2
Summary The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways SNARE interactions in vesicular transport

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