PRMT1 (Isoform 3) (1-353, His-MBP-tagged)

CAT#: AR09076PU-N

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Recombinant human PRMT1, fused to His-MBP tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.


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USD 260.00


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2 Weeks

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    • 100 ug


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Product Data
Description Recombinant human PRMT1, fused to His-MBP tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Species Human
Expression Host E. coli
Tag His-MBP-tag
Concentration 1.0 mg/ml (determined by Bradford assay)
Purity = 90 by SDS PAGE
Buffer 40 mM Tris pH 8.0, 100 mM NaCl, 4 mM MgCl2, 2 mM DTT, 40% glycerol
Bioactivity 10,000 unit/ml 10,000 unit/ml - Unit Definition: One unit will transfer 1pmol of methyl group to synthetic peptide of histone H4 for 10 minutes at 37°C.
Preparation Liquid purified protein
Reference Data
RefSeq NP_001193971
Locus ID 3276
Cytogenetics 19q13.33
Synonyms ANM1; HCP1; HRMT1L2; IR1B4
Summary This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]

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68 Mouse Clones