SPART (NM_001142294) Human Mass Spec Standard

CAT#: PH327155

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SPG20 MS Standard C13 and N15-labeled recombinant protein (NP_001135766)



  View other "SPART" proteins (15)

USD 2,712.00


Availability*
3 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description SPG20 MS Standard C13 and N15-labeled recombinant protein (NP_001135766)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC227155
Predicted MW 72.9 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001135766
RefSeq Size 4838
RefSeq ORF 1998
Synonyms SPG20; TAHCCP1
Locus ID 23111
UniProt ID Q8N0X7, A0A024RDV9
Cytogenetics 13q13.3
Summary This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]

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