ENSA (NM_207042) Human Mass Spec Standard
CAT#: PH320441
ENSA MS Standard C13 and N15-labeled recombinant protein (NP_996925)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC220441 |
Predicted MW | 15.1 kDa |
Protein Sequence |
>RC220441 representing NM_207042
Red=Cloning site Green=Tags(s) MSQKQEEENPAEETGEEKQDTQEKEGILPERAEEAKLKAKYPSLGQKPGGSDFLMKRLQKGDYKSLHWSV LLCADEMQKYFDSGDYNMAKAKMKNKQLPSAGPDKNLVTGDHIPTPQDLPQRKSSLVTSKLAGGQVE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_996925 |
RefSeq Size | 1300 |
RefSeq ORF | 411 |
Synonyms | ARPP-19e |
Locus ID | 2029 |
UniProt ID | O43768 |
Cytogenetics | 1q21.3 |
Summary | The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC404060 | ENSA HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC404105 | ENSA HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LC417988 | ENSA HEK293T cell transient overexpression lysate (as WB positive control) |
USD 134.00 |
|
LY404060 | Transient overexpression lysate of endosulfine alpha (ENSA), transcript variant 8 |
USD 436.00 |
|
LY404105 | Transient overexpression lysate of endosulfine alpha (ENSA), transcript variant 1 |
USD 436.00 |
|
LY417988 | Transient overexpression lysate of endosulfine alpha (ENSA), transcript variant 3 |
USD 436.00 |
|
PH309655 | ENSA MS Standard C13 and N15-labeled recombinant protein (NP_997051) |
USD 3,255.00 |
|
TP309655 | Recombinant protein of human endosulfine alpha (ENSA), transcript variant 8, 20 µg |
USD 867.00 |
|
TP320441 | Recombinant protein of human endosulfine alpha (ENSA), transcript variant 1, 20 µg |
USD 867.00 |
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