PRX (NM_020956) Human Mass Spec Standard

CAT#: PH316161

PRX MS Standard C13 and N15-labeled recombinant protein (NP_066007)

Product Images

Coomassie blue staining of purified PRX protein (Cat# TP316161). The protein was produced from HEK293T cells transfected with PRX cDNA clone (Cat# RC216161) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC216161
• Predicted MW: 15.8 kDa
• Protein Sequence:
  Sequence Link

  >RC216161 representing NM_020956
  Red=Cloning site Green=Tags(s)
  
  MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARV
  FFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGPRAKVAKL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_066007
• RefSeq Size: 5502
• RefSeq ORF: 383
• Synonyms: CMT4F
• Locus ID: 57716
• UniProt ID: Q9BXM0
• Cytogenetics: 19q13.2
• Summary: This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome