Caspase 9 (CASP9) (NM_032996) Human Mass Spec Standard

CAT#: PH313375

Reviews ()
Write a review

CASP9 MS Standard C13 and N15-labeled recombinant protein (NP_127463)



  View other "CASP9" proteins (6)

USD 2,260.00


Availability*
3 Weeks

Size
    • 10 ug


Product images

Specifications

Product Data
Description CASP9 MS Standard C13 and N15-labeled recombinant protein (NP_127463)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213375
Predicted MW 30 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_127463
RefSeq Size 1584
RefSeq ORF 798
Synonyms APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56
Locus ID 842
Cytogenetics 1p36.21
Summary This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Protein Families Druggable Genome, Protease, Stem cell - Pluripotency
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Endometrial cancer, Huntington's disease, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Parkinson's disease, Pathways in cancer, Prostate cancer, Small cell lung cancer, VEGF signaling pathway, Viral myocarditis

Documents

Other Versions

Other products for "CASP9"
Frequently bought together (2)
Transient overexpression lysate of caspase 9, apoptosis-related cysteine peptidase (CASP9), transcript variant beta
    • 100 ug

USD 360.00


Rabbit polyclonal Caspase 9 (Cleaved-Asp315) antibody
    • 100 ul

USD 345.00

Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Molbio tools