Jagged1(JAG1) (NM_000214) Human Mass Spec Standard

CAT#: PH310516

JAG1 MS Standard C13 and N15-labeled recombinant protein (NP_000205)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description JAG1 MS Standard C13 and N15-labeled recombinant protein (NP_000205)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210516
Predicted MW 133.6 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_000205
RefSeq Size 5896
RefSeq ORF 3654
Synonyms AGS; AHD; AWS; CD339; HJ1; JAGL1
Locus ID 182
Cytogenetics 20p12.2
Summary The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]
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