Jagged1(JAG1) (NM_000214) Human Recombinant Protein

CAT#: TP310516

Recombinant protein of human jagged 1 (Alagille syndrome) (JAG1)

Request Larger Size Package


 Product Datasheet for 'TP310516'

USD 680.00


Availability*
2 Weeks

Size
    • 20 ug

Product images

Specifications

Product Data
Description Recombinant protein of human jagged 1 (Alagille syndrome) (JAG1)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC210516. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 133.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq NP_000205
Locus ID 182
Refseq Size 5896
Cytogenetics 20p12.2
Refseq ORF 3654
Synonyms AGS; AHD; AWS; CD339; HJ1; JAGL1
Summary The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]
Protein Families
Protein Pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents