PHLDA3 (NM_012396) Human Mass Spec Standard

SKU
PH306751
PHLDA3 MS Standard C13 and N15-labeled recombinant protein (NP_036528)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206751
Predicted MW 13.9 kDa
Protein Sequence
Protein Sequence
>RC206751 protein sequence
Red=Cloning site Green=Tags(s)

MTAAATATVLKEGVLEKRSGGLLQLWKRKRCVLTERGLQLFEAKGTGGRPKELSFARIKAVECVESTGRH
IYFTLVTEGGGEIDFRCPLEDPGWNAQITLGLVKFKNQQAIQTVRARQSLGTGTLVS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_036528
RefSeq Size 1516
RefSeq ORF 381
Synonyms TIH1
Locus ID 23612
UniProt ID Q9Y5J5
Cytogenetics 1q32.1
Summary p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.UniProtKB/Swiss-Prot Function
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Other "PHLDA3" proteins (3)
SKU Description Size Price
LC415793 Lyophilized PHLDA3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415793 Transient overexpression lysate of pleckstrin homology-like domain, family A, member 3 (PHLDA3) (as WB positive control) 100 ug
$436.00
TP306751 Recombinant protein of human pleckstrin homology-like domain, family A, member 3 (PHLDA3), 20 µg 20 ug
$737.00

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