CYRIB (NM_016623) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC205660 |
| Predicted MW | 36.7 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_057707 |
| RefSeq Size | 3838 |
| RefSeq ORF | 972 |
| Synonyms | BM-009; CYRI; CYRI-B; FAM49B; L1 |
| Locus ID | 51571 |
| UniProt ID | Q9NUQ9 |
| Cytogenetics | 8q24.21 |
| Summary | Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling (PubMed:31285585, PubMed:30250061). Regulates chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions. Limits Rac1 mediated activation of the Scar/WAVE complex, focuses protrusion signals and regulates pseudopod complexity by inhibiting Scar/WAVE-induced actin polymerization (PubMed:30250061). Protects against Salmonella bacterial infection. Attenuates processes such as macropinocytosis, phagocytosis and cell migration and restrict sopE-mediated bacterial entry (PubMed:31285585). Restricts also infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes (By similarity). Involved in the regulation of mitochondrial dynamics and oxidative stress (PubMed:29059164).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "CYRIB" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC413876 | Lyophilized FAM49B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY413876 | Transient overexpression lysate of family with sequence similarity 49, member B (FAM49B) (as WB positive control) | 100 ug |
$436.00
|
|
| TP305660 | Recombinant protein of human family with sequence similarity 49, member B (FAM49B), 20 µg | 20 ug |
$867.00
|
|
Citations
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