DHRS11 (NM_024308) Human Mass Spec Standard

SKU
PH301307
DHRS11 MS Standard C13 and N15-labeled recombinant protein (NP_077284)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201307
Predicted MW 28.3 kDa
Protein Sequence
Protein Sequence
>RC201307 protein sequence
Red=Cloning site Green=Tags(s)

MARPGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCD
LSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERN
VDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLH
DKDPEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGDIQMRPTEQVT

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_077284
RefSeq Size 1608
RefSeq ORF 780
Synonyms ARPG836; SDR24C1; spDHRS11
Locus ID 79154
UniProt ID Q6UWP2
Cytogenetics 17q12
Summary Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta-hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones.UniProtKB/Swiss-Prot Function
Protein Families Druggable Genome, Transmembrane
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Other "DHRS11" proteins (3)
SKU Description Size Price
LC411327 Lyophilized DHRS11 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY411327 Transient overexpression lysate of dehydrogenase/reductase (SDR family) member 11 (DHRS11) (as WB positive control) 100 ug
$436.00
TP301307 Recombinant protein of human dehydrogenase/reductase (SDR family) member 11 (DHRS11), 20 µg 20 ug
$867.00

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