Plexin A1 (PLXNA1) (NM_032242) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC222057L1V

Lenti ORF particles, PLXNA1 (Myc-DDK tagged) - Human plexin A1 (PLXNA1), 200ul, >10^7 TU/mL

Product Images

RC222057L1 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC222057L1V particle to overexpress human PLXNA1-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Plexin A1
• Synonyms: NOV; NOVP; PLEXIN-A1; PLXN1
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_032242
• ORF Size: 5688 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222057).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_032242.3, NP_115618.3
• RefSeq Size: 9071 bp
• RefSeq ORF: 5691 bp
• Locus ID: 5361
• UniProt ID: Q9UIW2
• Cytogenetics: 3q21.3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance
• MW: 211.1 kDa
• Gene Summary: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).[UniProtKB/Swiss-Prot Function]