MARCH11 (MARCHF11) (NM_001102562) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC219988L1V

Lenti ORF particles, MARCH11 (Myc-DDK-tagged)-Human membrane-associated ring finger (C3HC4) 11 (MARCH11), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: MARCHF11
• Synonyms: MARCH-XI; MARCH11; RNF226
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001102562
• ORF Size: 1206 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC219988).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001102562.1
• RefSeq Size: 1528 bp
• RefSeq ORF: 1209 bp
• Locus ID: 441061
• UniProt ID: A6NNE9
• Cytogenetics: 5p15.1
• MW: 43.7 kDa
• Gene Summary: MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]).[supplied by OMIM, Apr 2010]