KIRREL 3 (KIRREL3) (NM_032531) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC211025L2V

Lenti ORF particles, KIRREL3 (mGFP-tagged) - Human kin of IRRE like 3 (Drosophila) (KIRREL3), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: KIRREL 3
• Synonyms: KIRRE; MRD4; NEPH2; PRO4502
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_032531
• ORF Size: 2334 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC211025).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_032531.2
• RefSeq Size: 3794 bp
• RefSeq ORF: 2337 bp
• Locus ID: 84623
• UniProt ID: Q8IZU9
• Cytogenetics: 11q24.2
• Protein Families: Transmembrane
• MW: 85.3 kDa
• Gene Summary: The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]