TWIST2 (NM_057179) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205006L2V

Lenti ORF particles, TWIST2 (mGFP-tagged) - Human twist homolog 2 (Drosophila) (TWIST2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: TWIST2
• Synonyms: AMS; BBRSAY; bHLHa39; DERMO1; FFDD3; SETLSS
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_057179
• ORF Size: 480 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205006).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_057179.1
• RefSeq Size: 1186 bp
• RefSeq ORF: 483 bp
• Locus ID: 117581
• UniProt ID: Q8WVJ9
• Cytogenetics: 2q37.3
• Protein Families: Druggable Genome, Transcription Factors
• MW: 18.1 kDa
• Gene Summary: The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found. [provided by RefSeq, Apr 2014]