WISP2 (CCN5) (NM_003881) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204636L1V

  • LentiORF®

Lenti ORF particles, WISP2 (Myc-DDK tagged) - Human WNT1 inducible signaling pathway protein 2 (WISP2), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro


Buy this product and get 50% off on the Lenti RapidTiter kit. Use Code: Rapid50

USD 1,000.00

2 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol CCN5
Synonyms CT58; CTGF-L; WISP2
Mammalian Cell Selection None
Vector pLenti-C-Myc-DDK
ACCN NM_003881
ORF Size 750 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC204636).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_003881.2
RefSeq Size 1433 bp
RefSeq ORF 753 bp
Locus ID 8839
UniProt ID O76076
Cytogenetics 20q13.12
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
MW 26.8 kDa
Gene Summary This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. [provided by RefSeq, Jul 2008]

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