KCNN4 (NM_002250) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204457L2V

Lenti ORF particles, KCNN4 (mGFP-tagged) - Human potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (KCNN4), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: KCNN4
• Synonyms: DHS2; hIKCa1; hKCa4; hSK4; IK; IK1; IKCA1; KCa3.1; KCA4; SK4
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_002250
• ORF Size: 1281 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204457).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002250.2
• RefSeq Size: 2240 bp
• RefSeq ORF: 1284 bp
• Locus ID: 3783
• UniProt ID: O15554
• Cytogenetics: 19q13.31
• Domains: SK_channel, CaMBD
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• MW: 47.7 kDa
• Gene Summary: The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008]