AlaRS (AARS) (NM_001605) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202136L2V

Lenti ORF particles, AARS (mGFP-tagged) - Human alanyl-tRNA synthetase (AARS), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: AlaRS
• Synonyms: AARS; CMT2N; DEE29; EIEE29
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_001605
• ORF Size: 2904 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202136).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001605.2
• RefSeq Size: 3344 bp
• RefSeq ORF: 2907 bp
• Locus ID: 16
• UniProt ID: P49588
• Cytogenetics: 16q22.1
• Domains: tRNA-synt_2c, DHHA1
• Protein Pathways: Aminoacyl-tRNA biosynthesis
• MW: 106.8 kDa
• Gene Summary: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq, Jul 2008]