Epoxide hydrolase (EPHX1) (NM_000120) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200621L1V

Lenti ORF particles, EPHX1 (Myc-DDK tagged) - Human epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: EPHX1
• Synonyms: EPHX; EPOX; HYL1; MEH
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_000120
• ORF Size: 1365 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200621).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000120.2
• RefSeq Size: 1847 bp
• RefSeq ORF: 1368 bp
• Locus ID: 2052
• UniProt ID: P07099
• Cytogenetics: 1q42.12
• Domains: abhydrolase
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Metabolism of xenobiotics by cytochrome P450
• MW: 52.9 kDa
• Gene Summary: Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2008]