Copa (NM_009938) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR222733L2V

Lenti ORF particles, Copa (GFP-tagged) - Mouse coatomer protein complex subunit alpha (Copa), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Copa
• Synonyms: AU040324; xenin
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_009938
• ORF Size: 3672 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR222733).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_009938.4, NP_034068.3
• RefSeq Size: 4629 bp
• RefSeq ORF: 3675 bp
• Locus ID: 12847
• UniProt ID: Q8CIE6
• Cytogenetics: 1 79.54 cM
• Gene Summary: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).[UniProtKB/Swiss-Prot Function]