c Kit (KIT) Mouse Monoclonal Antibody [Clone ID: UMAB216]
KIT mouse monoclonal antibody,clone UMAB216
Product Datasheet for 'UM800108'
|Recommend Dilution||IHC 1:400|
|Immunogen||Human recombinant protein fragment corresponding to amino acids 27-308 of human KIT(NP_000213) produced in E.coli.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Concentration||0.5~1.0 mg/ml (Lot Dependent)|
|Purification||Purified from cell culture supernatant by affinity chromatography|
|Predicted Protein Size||109.7 kDa|
|Gene Name||Homo sapiens KIT proto-oncogene, receptor tyrosine kinase (KIT), transcript variant 1, mRNA.|
|Background||This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]|
|Synonyms||C-Kit; CD117; PBT; SCFR|
|Protein Families||Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Protein Kinase, Stem cell - Pluripotency, Transmembrane|
|Protein Pathways||Acute myeloid leukemia, Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.