c Kit (KIT) Mouse Monoclonal Antibody [Clone ID: UMAB216]

USD 468.00


Availability*
In Stock

Size
    • 100 ul


Product images

Specifications

Product Data
Clone Name UMAB216
Applications IHC
Recommend Dilution IHC 1:400
Reactivity Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 27-308 of human KIT(NP_000213) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 109.7 kDa
Gene Name Homo sapiens KIT proto-oncogene receptor tyrosine kinase (KIT), transcript variant 1
Background This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms C-Kit; CD117; PBT; SCFR
Reference Data
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Protein Kinase, Stem cell - Pluripotency, Transmembrane
Protein Pathways Acute myeloid leukemia, Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer

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