TREM2 Rabbit Polyclonal Antibody

CAT#: TA890251S

TREM2 Rabbit Polyclonal Antibody

Product Images

Figure A, Western blot analysis of overexpressed lysates(15ug per lane) from HEK293T cells transfected with empty plasmid (PS100001, NC) ,human TREM2 recombinant protein( hTREM2),mouse TREM2 plasmid (MR228773, mTREM2), rat TREM2 plasmid (RR204747, rTREM2) using anti-TREM2 antibody TA890251(1:2000). Figure B, Western blot analysis of the same samples as figure A with anti-DDK antibody (TA180144, 1:1000)(NC,mTREM2,rTREM2) and anti-His antibody (TA150088, 1:500)(hTREM2)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length human recombinant protein of human TREM2 (NP_061838) produced in Expi 293F.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23.4 kDa
• Gene Name: triggering receptor expressed on myeloid cells 2
• Database Link:
  NP_061838
  Entrez Gene 54209 Human
  UniProt ID Q9NZC2
• Background: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
• Synonyms: PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane