p75 NGF Receptor (NGFR) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2A1]

CAT#: TA812991AM

NGFR mouse monoclonal antibody,clone OTI2A1, Biotinylated

Product Images

Flow cytometric analysis of living 293T cells transfected with NGFR overexpression plasmid (RC207966), Red)/empty vector (PS100001, Blue) using anti-NGFR antibody (TA812991). Cells incubated with a non-specific antibody (Green) were used as isotype control (1:100).

Specifications

Product Data

• Clone Name: OTI2A1
• Applications: FC
• Recommended Dilution: FLOW 1:100
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human Ngfr (NP_002498) produced in HEK293T cell.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45.18 kDa
• Gene Name: nerve growth factor receptor
• Database Link:
  NP_002498
  Entrez Gene 18053 MouseEntrez Gene 24596 RatEntrez Gene 4804 Human
  UniProt ID P08138
• Background: Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]
• Synonyms: CD271; Gp80-LNGFR; p75(NTR); p75NTR; TNFRSF16

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Neurotrophin signaling pathway