DUSP5 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2F8]
CAT#: TA811034AM
DUSP5 mouse monoclonal antibody,clone OTI2F8, Biotinylated
Conjugation: Unconjugated HRP
USD 200.00
Specifications
Product Data | |
Clone Name | OTI2F8 |
Applications | WB |
Recommended Dilution | WB 1:500 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 125-384 of human DUSP5 (NP_004410) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 41.9 kDa |
Gene Name | dual specificity phosphatase 5 |
Database Link | |
Background | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008] |
Synonyms | DUSP; HVH3 |
Reference Data | |
Protein Families | Phosphatase |
Protein Pathways | MAPK signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF811034 | Carrier-free (BSA/glycerol-free) DUSP5 mouse monoclonal antibody,clone OTI2F8 |
USD 600.00 |
|
TA811034 | DUSP5 mouse monoclonal antibody,clone OTI2F8 |
USD 447.00 |
|
TA811034BM | DUSP5 mouse monoclonal antibody,clone OTI2F8, HRP conjugated |
USD 509.00 |
|
TA811034S | DUSP5 mouse monoclonal antibody,clone OTI2F8 |
USD 200.00 |
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