MAD4 (MXD4) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI5E6]

CAT#: TA808855BM

MXD4 mouse monoclonal antibody,clone OTI5E6, HRP conjugated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MXD4 (RC209651, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MXD4 (1:2000). Positive lysates LY416638 (100ug) and LC416638 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI5E6
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human MXD4(NP_006445) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: HRP
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23.3 kDa
• Gene Name: MAX dimerization protein 4
• Database Link:
  NP_006445
  Entrez Gene 17122 MouseEntrez Gene 10608 Human
  UniProt ID Q14582
• Background: This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008]
• Synonyms: bHLHc12; MAD4; MST149; MSTP149

Reference Data

• Protein Families: Druggable Genome, Transcription Factors