LNX1 Mouse Monoclonal Antibody [Clone ID: OTI1H9]

CAT#: TA800747

LNX1 mouse monoclonal antibody, clone OTI1H9 (formerly 1H9)

Product Images

Figure A, Western blot analysis of overexpressed lysates(15ug per lane) from HEK293T cells transfected with empty plasmid (PS100001, NC) , human LNX1 plasmid (RC206386, hLNX1), mouse LNX1 plasmid (MR219190, mLNX1) using anti-LNX1 antibody TA800747 (1:500). Figure B, Western blot analysis of the same samples as figure A with anti-DDK antibody (TA180144, 1:1000)

Specifications

Product Data

• Clone Name: OTI1H9
• Applications: WB
• Recommended Dilution: WB 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 260-528 of human LNX1 (NP_116011) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 69.5 kDa
• Gene Name: ligand of numb-protein X 1
• Database Link:
  NP_116011
  Entrez Gene 84708 Human
  UniProt ID Q8TBB1
• Background: This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: LNX; MPDZ; PDZRN2

Reference Data

• Protein Families: Druggable Genome