OSBPL2 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2E6]

CAT#: TA800553AM

OSBPL2 mouse monoclonal antibody,clone 2E6, Biotinylated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Cat# PS100001, Left lane) or pCMV6-ENTRY OSBPL2 (Cat# RC201344, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OSBPL2(Cat# TA800553). Positive lysates LY408266 (100ug) and LC408266 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI2E6
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 258-480 of human OSBPL2 (NP_653081) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: oxysterol binding protein like 2
• Database Link:
  NP_653081
  Entrez Gene 228983 MouseEntrez Gene 296461 RatEntrez Gene 9885 Human
  UniProt ID Q9H1P3
• Background: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
• Synonyms: DFNA67; DNFA67; ORP-2; ORP2