Adenylate Kinase 1 (AK1) Rabbit Polyclonal Antibody

CAT#: TA590022

Rabbit Polyclonal Adenylate Kinase 1 Antibody

Product Images

ELISA: Adenylate Kinase 1 Antibody

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  Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-AK1 polyclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

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  Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-AK1 rabbit polyclonal antibody. (TA590022)

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  Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-AK1 rabbit polyclonal antibody. (TA590022)

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  Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-AK1 rabbit polyclonal antibody. (TA590022)

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Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB 1:5000, IHC 1:150,ELISA 1:100-1:2000
• Reactivities: Human, Dog, Monkey, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DNA immunization. This antibody is specific for the C Terminus Region of the target protein.
• Formulation: 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
• Concentration: 1.03mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adenylate kinase 1
• Database Link:
  NP_000467
  Entrez Gene 11636 MouseEntrez Gene 480712 DogEntrez Gene 706338 MonkeyEntrez Gene 203 Human
  UniProt ID P00568
• Background: Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
• Synonyms: HTL-S-58j
• Note: This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Purine metabolism