ATRIP Mouse Monoclonal Antibody [Clone ID: OTI1F10]

CAT#: TA504586S

ATRIP mouse monoclonal antibody, clone OTI1F10 (formerly 1F10)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATRIP (RC223562, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATRIP. Positive lysates LY408977 (100ug) and LC408977 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI1F10
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 42-309 of human ATRIP(NP_569055) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.66 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 85.7 kDa
• Gene Name: ATR interacting protein
• Database Link:
  NP_569055
  Entrez Gene 84126 Human
  UniProt ID Q8WXE1
• Background: The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: DKFZp762J2115; FLJ12343; MGC20625; MGC21482; MGC26740