UNG Mouse Monoclonal Antibody [Clone ID: OTI2C12]

CAT#: TA503563

UNG mouse monoclonal antibody, clone OTI2C12 (formerly 2C12)

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 Product Datasheet for 'TA503563'

USD 350.00

In Stock

    • 100 ul


Product Data
Clone Name OTI2C12
Applications WB, IHC, IF
Recommend Dilution WB 1:500~2000, IHC 1:150, IF 1:100,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human UNG(NP_550433) produced in HEK293T cell.
Isotype IgG2b
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.42 mg/ml
Purification Purified from mouse ascites fluids by affinity chromatography
Predicted Protein Size 34.5 kDa
Gene Name uracil DNA glycosylase
Background This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq].
Reference Data
Protein Families Stem cell - Pluripotency, Druggable Genome
Protein Pathways Base excision repair, Primary immunodeficiency
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