CD51 (ITGAV) Rabbit Polyclonal Antibody

CAT#: TA392852

Integrin αV (P804) polyclonal antibody

Product Images

Western blot (WB) analysis of Integrin αV (P804) pAb at 1:1000 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:C6 whole cell lysate(20ug) Lane3:CT26 whole cell lysate(40ug)

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  Immunohistochemistry (IHC) analyzes of Integrin αV (P804) pAb in paraffin-embedded human brain tissue.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:1000 IHC: 1:50~1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 771-820 of Human Integrin αV.
• Specificity: Integrin αV (P804) polyclonal antibody detects endogenous levels of Integrin αV protein.
• Formulation: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Predicted Protein Size: ~ 116 kDa
• Gene Name: integrin subunit alpha V
• Database Link:
  Entrez Gene 3685 Human
  UniProt ID P06756
• Background: The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlaping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with extracellular environment (inside-out signaling).Several αV subfamily members, including αVβ3, αVβ5, αVβ1, are highly expressed in active endothelial cells and cancer cells where they play a critical role in angiogenesis and tumor metastasis.
• Synonyms: CD51; Integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; ITGAV; MSK8; Vitronectin receptor subunit alpha; VNRA
• Note: For research use only, not for use in diagnostic procedure.