LAMP1 Rabbit Polyclonal Antibody

CAT#: TA392480

CD107a/LAMP1 polyclonal antibody

Product Images

Western blot (WB) analysis of CD107a/LAMP1 polyclonal antibody at 1:1000 dilution Lane1:The Stomach tissue lysate of Mouse(30ug) Lane2:The Kidney tissue lysate of Rat(30ug) Lane3:HCT116 whole cell lysate(30ug) Lane4:HEK293T whole cell lysate(30ug)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000~1:2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to Human CD107a/LAMP1.
• Specificity: CD107a/LAMP1 polyclonal antibody detects endogenous levels of CD107a/LAMP1 protein.
• Formulation: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Predicted Protein Size: ~ 95 kDa
• Gene Name: lysosomal associated membrane protein 1
• Database Link:
  Entrez Gene 3916 Human
  UniProt ID P11279
• Background: Lysosome-associated membrane protein 1 and 2 (LAMP1 and LAMP2) are two abundant lysosomal membrane proteins. Both are transmembrane proteins and are heavily glycosylated at the amino-terminal luminal side of the lysosomal inner leaflet, which protects the proteins from proteolysis. The carboxy terminus of LAMP1 is exposed to the cytoplasm and contains a tyrosine sorting motif that targets LAMP to lysosomal membranes. LAMP1 and LAMP2 are 37% homologous in their protein sequences. Both LAMP1 and LAMP2 are involved in regulating lysosomal motility during lysosome-phagosome fusion and cholesterol trafficking.
• Synonyms: CD107 antigen-like family member A; CD107a; LAMP-1; LAMP1; Lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane protein 1
• Note: For research use only, not for use in diagnostic procedure.