Il10 Rabbit Polyclonal Antibody

CAT#: TA389640

IL10 Rabbit pAb

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB,1:1000 - 1:5000
• Reactivities: Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: PBS with 0.05% proclin300,50% glycerol,pH7.3.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 10
• Database Link:
  Entrez Gene 16153 Mouse
  UniProt ID P18893
• Background: This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis.
• Synonyms: CSIF; IL-10; IL10A; MGC126450; MGC126451; TGIF