Cd96 Rabbit Monoclonal Antibody [Clone ID: 6A6]

CAT#: TA386298

Recombinant Anti-CD96 (Clone 6A6)

Specifications

Product Data

• Clone Name: 6A6
• Applications: Bl, FC
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Monoclonal
• Immunogen: This antibody was raised by immunising rats with murine CD96.
• Specificity: This antibody is specific for murine CD96, and recognises an epitope in the first Ig domain.
  
  This antibody blocks murine CD96-CD155 interaction, and has been shown to bind to the first Ig domain of CD96 and compete with CD155 binding (Roman Aguilera et al, 2018). This antibody displays significant anti-metastatic activity in four experimental lung metastases models and one spontaneous tumour metastasis model (Roman Aguilera et al, 2018), with a potency greater than the anti-CD96 monoclonal antibodies 3.3 and 8B10. The binding specificity of this antibody has been determined in flow cytometric analysis of HEK-293 cells transfected with a range of CD96 Ig domain chimeric constructs (Roman Aguilera et al, 2018).
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: CD96 antigen
• Database Link:
  Entrez Gene 84544 Mouse
  UniProt ID Q3U0X8
• Synonyms: DKFZp667E2122; MGC22596; TACTILE
• Note: This chimeric rabbit antibody was made using the variable domain sequences of the original rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.