Superoxide Dismutase 1 (SOD1) Rabbit Monoclonal Antibody [Clone ID: R07-1G6]

CAT#: TA385301

Superoxide Dismutase 1 Rabbit monoclonal Antibody

Product Images

Western blot analysis of Superoxide Dismutase 1 in K562, rat Brain, C6, 3T3, Hela lysates using Superoxide Dismutase 1 antibody.

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  Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Superoxide Dismutase 1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Specifications

Product Data

• Clone Name: R07-1G6
• Applications: IHC, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Superoxide Dismutase 1
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 16 kDa; Observed MW: 18 kDa
• Gene Name: superoxide dismutase 1, soluble
• Database Link:
  Entrez Gene 6647 Human
  UniProt ID P00441
• Background: Swiss-Prot Acc.P00441.Destroys radicals which are normally produced within the cells and which are toxic to biological systems.MiscellaneousThe protein (both wild-type and ALS1 variants) has a tendency to form fibrillar aggregates in the absence of the intramolecular disulfide bond or of bound zinc ions. These aggregates may have cytotoxic effects. Zinc binding promotes dimerization and stabilizes the native form.
• Synonyms: ALS1; homodimer; IPOA; SOD