Phospholipase C gamma 1 (PLCG1) Rabbit Polyclonal Antibody

CAT#: TA384993

PLCG1 Rabbit polyclonal Antibody

Product Images

Western blot analysis of PLC gamma 1 in Jurkat lysates using PLCG1 antibody.

Specifications

Product Data

• Applications: IF, IP, WB
• Recommended Dilution: WB: 1/1000-1/5000
  ICC/IF: 1/50-1/200
  IP: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human PLCG1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 149kDa
• Gene Name: phospholipase C gamma 1
• Database Link:
  Entrez Gene 5335 Human
  UniProt ID P19174
• Background: Swiss-Prot Acc.P19174.The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras.
• Synonyms: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; inositoltrisphosphohydrolase; NCKAP3; OTTHUMP00000178982; PLC-148; PLC-gamma-1; PLC-II; PLC1; PLC148; PLCgamma1