CD146 (MCAM) Rabbit Polyclonal Antibody

CAT#: TA384761

CD146 Rabbit polyclonal Antibody

Product Images

Western blot analysis of CD146 in (1) A375 lysates;(2) HUVEC lysates using CD146 antibody.

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  Immunohistochemistry analysis of paraffin-embedded Human uterus using CD146 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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  Immunofluorescence analysis of CD146 in A375 using CD146 antibody.

Specifications

Product Data

• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/50
  FC: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human CD146
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 72kDa
• Gene Name: melanoma cell adhesion molecule
• Database Link:
  Entrez Gene 4162 Human
  UniProt ID P43121
• Background: Swiss-Prot Acc.P43121.CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development.
• Synonyms: CD146; Gicerin; MUC18