JNK1 (MAPK8) Rabbit Polyclonal Antibody

CAT#: TA384739

JNK1/3 Rabbit polyclonal Antibody

Product Images

Western blot analysis of JNK1/JNK3 in HeLa lysates using JNK1/3 antibody.

Specifications

Product Data

• Applications: IP, WB
• Recommended Dilution: WB: 1/1000-1/2000
  IP: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human JNK1/JNK3
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 46,54kDa
• Gene Name: mitogen-activated protein kinase 8
• Database Link:
  Entrez Gene 5599 Human
  UniProt ID P45983
• Background: Swiss-Prot Acc.P45983,P53779.The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, by growth factors and GPCR agonists. As with the other MAPKs, the core signaling unit is composed of a MAPKKK, typically MEKK1-MEKK4, or by one of the mixed lineage kinases (MLKs), which phosphorylate and activate MKK4/7.
• Synonyms: JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; OTTHUMP00000019552; PRKM8; SAPK1