MEK1 (MAP2K1) Rabbit Polyclonal Antibody

CAT#: TA384707

MEK1/2 Rabbit polyclonal Antibody

Product Images

Western blot analysis of MEK1/2 in (1) 293T lysates; (2) A549 lysates using MEK1/2 antibody.

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  Immunohistochemistry analysis of paraffin-embedded Human kidney using MEK1/2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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  Immunofluorescence analysis of MEK1/2 in Hela using MEK1/2 antibody.

Specifications

Product Data

• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/100-1/500
  ICC/IF: 1/50-1/100
  IP: 1/50-1/100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human MEK1/2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 44kDa
• Gene Name: mitogen-activated protein kinase kinase 1
• Database Link:
  Entrez Gene 5604 Human
  UniProt ID Q02750
• Background: Swiss-Prot Acc.Q02750,P36507.Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2.
• Synonyms: MAPKK1; MEK1; MKK1; PRKMK1