H1-8 Rabbit Polyclonal Antibody

CAT#: TA384360

Histone H1.8 Rabbit polyclonal Antibody

Product Images

Immunofluorescence analysis of Histone H1.8 in HeLa cells using Histone H1.8 antibody. Sample with blocking peptide on the right.

Specifications

Product Data

• Applications: ELISA, IF, IHC
• Recommended Dilution: IHC: 1/100-1/300
  IF: 1/200-1/1000
  ELISA: 1/10000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized peptide derived from human Histone H1. AA range:131-180
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Database Link:
  UniProt ID Q8IZA3
• Background: Swiss-Prot Acc.Q8IZA3.May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling .