CHRM2 Rabbit Monoclonal Antibody [Clone ID: R01-9B9]

CAT#: TA383998

Muscarinic Acetylcholine Receptor M2 Rabbit monoclonal Antibody

Product Images

Western blot analysis of Muscarinic Acetylcholine Receptor 2/CM2 in K562, C6, Hela lysates using Muscarinic Acetylcholine Receptor M2 antibody.

Specifications

Product Data

• Clone Name: R01-9B9
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/20-1/100
  IP: 1/20-1/50
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Muscarinic Acetylcholine Receptor 2
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 52 kDa; Observed MW: 52 kDa
• Gene Name: cholinergic receptor muscarinic 2
• Database Link:
  Entrez Gene 1129 Human
  UniProt ID P08172
• Background: Swiss-Prot Acc.P08172.The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
• Synonyms: FLJ43243; HM2; MGC120006; MGC120007; OTTHUMP00000208394; OTTHUMP00000208395