Caspase 1 (CASP1) Rabbit Polyclonal Antibody

CAT#: TA383870

Caspase 1 Rabbit polyclonal Antibody


USD 380.00

4 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications ELISA, IHC, WB
Recommended Dilution WB: 1/500-1/2000
IHC: 1/100-1/300
ELISA: 1/20000
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The antiserum was produced against synthesized peptide derived from human Caspase 1. AA range:342-391
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Stability 1 year
Predicted Protein Size Observed MW:45kDa
Gene Name caspase 1
Background Swiss-Prot Acc.P29466.Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive
Synonyms CASP-1; caspase-1; ICE; IL-1BC; IL1B-convertase; IL1BC; IL1BCE; p45
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.